Now that we know what HGH is, what does it do? This protein we call HGH is produced in the pituitary gland which is in the brain. The HGH is produced there and sent off to the liver where it stimulates the liver to produce IGF-1 and other insulin growth factors. Insulin-like growth factor-1 (IGF-1) stimulates the growth of muscle and bones while also repairing damaged tissue. It will repair muscle, tendons, ligaments and other tissue. HGH is also instrumental in cell regeneration, immune system support, and cardiovascular health. It also aids in repairing damaged organ tissue. As we grow into adulthood, HGH is responsible for keeping our muscles from wasting away. It supports our healthy immune system responses and regulates aspects of our metabolic functions. HGH deals with increased fat metabolism and healthy body composition later in life. HGH maintains and repairs our skin and other tissues. That might sound like a list that is too good to be true. So, HGH will repair all these problems that are associated with aging? The answer is yes! Medical science has proven these benefits over and over.
Unfortunately HGH is not approved for these uses in most countries. Fortunately, you found Regenamex Clinic. After our doctor makes the preliminary laboratory studies, he will make a program tailored to your needs and we can get you the top brand pharmaceutical HGH, dose and price that makes sense. Levels of HGH in our bodies usually peak while we are in adolescence. HGH then begins to decline during our early 30’s. After 30 HGH production typically declines by 25% each decade. By the time we reach or ’60s HGH being produced daily is as low as 10% of what it was during our youth! This then produces the age markers listed below
Fortunately, Hormone Replacement Therapy (HRT) can reverse or improve these symptoms in patients that engage in this therapy. This is why you will often hear references with respect to HGH as “The Fountain of Youth” It can present a better quality of life for those of us aging, as well as provide many other great benefits. HGH is the only substance that can actually initiate hyperplasia, which equates to new muscle cells. While the use of anabolic steroids can cause hypertrophy (the enlargement of existing muscle cells), Steroids do not offer the ability to produce more muscle cells while HGH can. HGH also increases protein synthesis, which can be responsible for growing muscle cells. HGH strengthens and heals connective tissues, cartilage, and tendons. This Means you will heal faster and that is what builds bigger and better muscles. These benefits are what make it so attractive to athletes in all sports.
Human growth hormone (HGH – somatropin/somatotropin is one of the most abundant hormones secreted by the anterior lobe of the pituitary gland or otherwise known as the Hypophysis. Once growth hormone is released by the pituitary gland it is quickly taken in by the liver and converted into growth factors, the most important growth factor is the one called IGF-1. These growth factors are the messengers that carry the signals or messages to the cells of the body. This communication regulates the growth of cells, telling them when to live and when to die. Cellular reproduction slows unless the cells are prompted by the growth factors of HGH and IFG-1. During the growth and development stage of life, the human growth hormone is responsible for the proper growth and development of our muscles and bones.
However once adulthood is reached HGH slows production which causes our bodies to change as we age, increase in belly fat, sagging skin, increased immune disorders, and that is what we strive to curve; the process of our bodies aging as we grow older. The importance of HGH is that it affects almost every cell of our body and helps to keep the cells and systems healthy. Healthy levels of HGH account for things such as good muscle/fat ratio, a high libido, good sexual function, energy and endurance, good muscle tone, menopause, improved sleep, increased bone density, regulates our blood pressure and better overall skin. As we age the function of the pituitary gland releases lower and lower amounts of HGH into the bloodstream for the body to use. Therefore we inject biosynthetic somatropin which is an exact replica of what our bodies produce, back into the endocrine system to slow and reverse these aging symptoms.
HGH is short-lived, but during its short half-hour activity per burst from the pituitary gland, it exerts itself through direct and indirect effects. Its direct effects are the result of the HGH binding its receptor on target cells. Fat cells (adipocytes), as well as myocytes (muscle cells), have HGH receptors. On fat cells, HGH stimulates them to break down triglycerides and suppresses the fat ability to uptake circulating lipids. HGH BREAKS DOWN FAT CELLS and the fat cells have receptors for the HGH to bind to! Take HGH and lose fat.
Its indirect effects are in the process we described in the section above. When HGH travels to the liver secretes IGF-1. When this IGF-1 is secreted, it stimulates the proliferation of chondrocytes (cartilage cells), which result in bone growth. It also plays a part in stimulating both the proliferation and differentiation of myoblasts (the precursor to skeletal muscle fibers). IGF-1 also stimulates amino acid uptake and protein synthesis in muscle and other tissues. The easy way to look at this is that your bones and cartilage get stronger. A lot of people worry that HGH is going to make their bones grow a lot and their skulls will get thicker and all kinds of weird growth. That does not happen unless you really abuse your dose. We typically prescribe 2 – 4 IU a day. You would have to take over 10 IU a day for years to have dramatic bone growth.
HGH stimulates protein anabolism in many tissues. This reflects increased protein synthesis, decreased oxidation of proteins, and increased amino acid uptake. You need protein synthesis to grow bigger muscles. So easy translation is that HGH helps you build more muscle. It will not get you results like steroids, but it will double how much muscle you could put on in a year naturally. HGH – Structure The major isoform of the human growth hormone is a protein of 191 amino acids and a molecular weight of 22,124 daltons. The structure includes four helices necessary for functional interaction with the GH receptor. It appears that in structure GH is evolutionarily homologous to prolactin and chorionic somatomammotropin. Despite marked structural similarities between growth hormone from different species, only human and primate growth hormones have significant effects on humans. Several molecular isoforms of GH exist in the pituitary gland and are released to blood. In particular, a variant of approximately 20 kDa originated by alternative splicing is present in a rather constant 1:9 ratio, while recently an additional variant of ~ 23-24 kDa has also been reported in post-exercise states at higher proportions. This variant has not been identified, but it has been suggested to coincide with a 22 kDa glycosylated variant of 23 kDa identified in the pituitary gland. Furthermore, these variants circulate partially bound to a protein (growth hormone-binding protein, GHBP), which is the truncated part of the growth hormone receptor, and an acid-labile subunit (ALS).
This is way above most people’s heads but in here for the science geeks and doctors out there. Non-medical use of hGH in Athletic Enhancement Athletes in many sports have used human growth hormone in order to attempt to enhance their athletic performance. There have been studies recently that try to say this isn’t true. So then if it doesn’t improve athletic ability, why is it prohibited in most professional sports? I think this makes it pretty clear that HGH works as a performance-enhancing drug. We have posted a great study that shows it does improve athletic performance. In a study labeled, “ From Worst to First .” A team of researchers found that HGH is so beneficial to endurance that the worst athlete in an Olympic race would most likely with the next race with HGH use if the other athletes did not use it also.
History of use and manufacture of GH as a drug The identification, purification and later synthesis of growth hormone is associated with Choh Hao Li. Genentech pioneered the first use of recombinant human growth hormone for human therapy in 1981. Prior to its production by recombinant DNA technology, the growth hormone used to treat deficiencies was extracted from the pituitary glands of cadavers. Attempts to create a wholly synthetic HGH failed. Limited supplies of HGH resulted in the restriction of HGH therapy to the treatment of idiopathic short stature. The growth hormone from other primates was found to be inactive in humans.
In 1985, unusual cases of Creutzfeldt-Jacob disease were found in individuals that had received cadaver-derived HGH ten to fifteen years previously. Based on the assumption that infectious prions causing the disease were transferred along with the cadaver-derived HGH, cadaver-derived HGH was removed from the market. In 1985, biosynthetic human growth hormone replaced pituitary-derived human growth hormone for therapeutic use in the U.S. and elsewhere. As of 2005, recombinant growth hormones available in the United States (and their manufacturers) included Humatrope (Lilly), Genotropin (Pfizer), Norditropin (Novo), and Saizen (Merck).
● Diabetic retinopathy (a serious eye condition caused by diabetes) or cancer / or Prader-Willi syndrome and are also overweight or have sleep apnea or severe respiratory (lung) problems.
You should also not use somatropin if you have a serious medical condition after having:
● Open heart surgery or stomach surgery/trauma or other medical emergency/breathing problems (such as lung failure). If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication.
Before using somatropin, tell your doctor if you have:
NOTE : FDA pregnancy category B. Some brands of somatropin are not expected to harm an unborn baby, including Genotropin, Omnitrope, Saizen, Serostim, Zorbtive and other approved 191 versions of rhgh. FDA pregnancy category C. It is not known whether certain other brands of somatropin will harm an unborn baby, including Humatrope or Norditropin. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether somatropin passes into breast milk or if it could harm a nursing baby. Do not use somatropin without telling your doctor if you are breast-feeding a baby.
NOTE : Effective Human Growth Hormone (HGH) is only available in injectable form. HGH in tablets, capsules, gel, cream or spray form are not as effective as the one that goes directly to your system injected subcutaneously.
Our programs offer a legal option that allows you to get the treatment you need for a fraction of the price in the US and Canada.